Shylaja Srinivasan, MD

Pediatric endocrinologist

Dr. Shylaja Srinivasan is a pediatric endocrinologist who cares for children with thyroid or adrenal disorders, endocrine conditions related to growth and puberty, bone and calcium disorders, and type 1 or type 2 diabetes. She has a special interest in type 2 diabetes that develops in childhood, an increasingly common condition caused by a complex interplay between genetics and environment.

Srinivasan's research focuses on understanding the genetic factors in type 2 diabetes. Her research also explores the genetic basis for different responses to diabetes medications, particularly metformin.

Originally from Chennai in South India, Srinivasan earned her medical degree at the Pondicherry Institute of Medical Sciences. She completed residencies in pediatrics at SUNY Downstate Health Sciences University and Tufts Medical Center, followed by a Harvard Medical School fellowship in pediatric endocrinology at Massachusetts General Hospital.

In 2016, Srinivasan won the Pediatric Endocrine Society's Clinical Scholar Award, receiving a grant to pursue research in the genetics of type 2 diabetes. She is a member of the Pediatric Endocrine Society, Endocrine Society, American Diabetes Association and American Society of Human Genetics.


Endocrinology Clinic
1825 Fourth St., Sixth Floor
San Francisco, CA 94158
Phone: (415) 353-7337
Fax: (415) 476-8214

Madison Clinic for Pediatric Diabetes
1500 Owens St., Suite 300
San Francisco, CA 94158
Phone: (415) 514-6234
Fax: (415) 353-2811

More about Shylaja Srinivasan

Additional Languages



Pondicherry Institute of Medical Sciences 2008


SUNY Downstate Health Sciences University, Pediatrics 2012
Tufts Medical Center, Pediatrics 2013


Massachusetts General Hospital, Pediatric Endocrinology 2016

Selected Research and Publications

  1. Todd JN, Srinivasan S, Pollin TI. Advances in the Genetics of Youth-Onset Type 2 Diabetes. Curr Diab Rep. 2018 Jun 22; 18(8):57.
  2. Srinivasan S, Yee SW, Giacomini KM. Pharmacogenetics of Antidiabetic Drugs. Adv Pharmacol. 2018; 83:361-389.
  3. Srinivasan S, Kaur V, Chamarthi B, Littleton KR, Chen L, Manning AK, Merino J, Thomas MK, Hudson M, Goldfine A, Florez JC. TCF7L2 Genetic Variation Augments Incretin Resistance and Influences Response to a Sulfonylurea and Metformin: The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH). Diabetes Care. 2018 Jan 11.
  4. Srinivasan S., Yee SW., Giacomini K . In Advances in Pharmacology, Elsevier. The Pharmacogenetics of Anti-Diabetic Drugs. 2018; 361-381.
  5. Srinivasan S., Levitsky L. Radovick and Misra’s Pediatric Endocrinology: A Practical Clinical Guide, Springer International. Type 2 diabetes in youth. 2018; 737-754.
  6. Srinivasan S, O'Rourke J, Bersche Golas S, Neumeyer A, Misra M. Calcium and Vitamin D Supplement Prescribing Practices among Providers Caring for Children with Autism Spectrum Disorders: Are We Addressing Bone Health? Autism Res Treat. 2016; 2016:6763205.
  7. Srinivasan S, Florez JC. Therapeutic Challenges in Diabetes Prevention: We Have Not Found the "Exercise Pill". Clin Pharmacol Ther. 2015 Aug; 98(2):162-9.
  8. Srinivasan S, Misra M. Hyperthyroidism in children. Pediatr Rev. 2015 Jun; 36(6):239-48.
  9. Kaplowitz P, Srinivasan S, He J, McCarter R, Hayeri MR, Sze R. Comparison of bone age readings by pediatric endocrinologists and pediatric radiologists using two bone age atlases. Pediatr Radiol. 2011 Jun; 41(6):690-3.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.